History of alcohol abuse reduces response to antipsychotics in people with first episode psychosis.
نویسنده
چکیده
Patients: 262 people aged 16–40 years, with schizophrenia, schizophreniform or schizoaffective disorder (DSM-IV), presenting with first episode psychosis. Participants scored >4 on the Positive and Negative Syndrome Scale (PANSS) and had a Clinical Global Impression (CGI) severity score >4. Exclusions: substance use in previous month, received antipsychotic drugs for more than 16 weeks, unstable medical illness, or high risk of suicide.
منابع مشابه
Persistent Psychosis after Abuse of High Dose of Zolpidem
Background: Zolpidem is a non-benzodiazepine medication which selectively affects GABAA receptors and treats insomnia. There are numerous reports of psychosis following the consumption of zolpidem all of which recovered after stopping the medication. Case Report: A 27 year old male law student, who was treated with 10 mg zolpidem due to insomnia, increased the dosage to 500 mg during 3 months. ...
متن کاملبررسی ویژگیهای دموگرافیک، بیماری و درمان در بیماران
Background and Aim: In recent years, a number of studies have been done on patients with first-episode of psychosis. The importance of this issue is to improve outcome of the psychosis. Due to lack of similar research in Iran and differences in culture as well as in treatment program, investigation of demographic characteristics and treatment of patients with first-episode of psychosis could be...
متن کاملSubstance use in a population-based clinic sample of people with first-episode psychosis.
BACKGROUND Substance use is implicated in the cause and course of psychosis. AIMS To characterise substance and alcohol use in an epidemiologically representative treatment sample of people experiencing a first psychotic episode in south Cambridgeshire. METHOD Current and lifetime substance use was recorded for 123 consecutive referrals to a specialist early intervention service. Substance ...
متن کاملFirst episode schizophrenia-related psychosis and substance use disorders: acute response to olanzapine and haloperidol.
BACKGROUND Co-occurring substance use disorders, mostly involving alcohol, cannabis or cocaine, occur commonly in patients with schizophrenia and are associated with increased morbidity and mortality. Available but limited data suggest that substance use disorders (especially cannabis use disorders) may also be common in first-episode patients and appear linked to a poor outcome in these patien...
متن کاملتأخیر در درمان و مسیر مراجعه بیماران دچار پسیکوز بار اول
AbstractObjectives: The aim of this study was investigation the duration of untreated psychosis (DUP), associated factors and pathways to care among patients with first episode psychosis admitted to Roozbeh Hospital. Method: In this cross-sectional study, 91 patients with the diagnosis of first episode psychosis admitted to Roozbeh Hospital in Tehran, were assessed regarding the duration of unt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Evidence-based mental health
دوره 7 3 شماره
صفحات -
تاریخ انتشار 2004